Abstract #0113
Carotid Multicontrast Atherosclerosis Characterization (MATCH) in a Single Scan: Technical Development and Preliminary Validation
Zhaoyang Fan 1 , Yibin Xie 1,2 , Wei Yu 3 , Antonio H. Conte 1 , Xiaoming Bi 4 , Yutaka Natsuaki 4 , Gerhard Laub 4 , Jing An 5 , Prediman K. Shah 1 , and Debiao Li 1
1
Cedars-Sinai Medical Center, Los Angeles,
CA, United States,
2
University
of California, Los Angeles, CA, United States,
3
Anzhen
Hospital, Beijing, China,
4
MR R&D Siemens
Healthcare, Los Angeles, CA, United States,
5
MR
Collaborations NE Asia, Siemens Healthcare, Beijing,
China
The conventional MRI protocol for the characterization
of atherosclerotic plaques involves a series of scans
that provide multiple contrast weightings. Despite the
success in previous investigations, it has some major
limitations such as limited slice resolution,
substantially long examination time, image registration
needed due to interscan motion. This work developed a 3D
MRI technique that acquires multiple image sets in a
single 5-minute scan with distinct contrast weightings
that help simplify compositional analysis in carotid
plaques. Preliminary healthy volunteer and patient
studies were performed to demonstrate the promise of
this technique in a clinical setting.
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