Terrence Jao1,
Hung Phi Do2, Krishna S. Nayak3
1Biomedical
Engineering, University of Southern California, Los Angeles, CA, United
States; 2Department of Physics, University of Southern California,
Los Angeles, CA, United States; 3Electrical Engineering, University
of Southern California, Los Angeles, CA, United States
Myocardial arterial spin labeling (ASL) is a technique for measuring myocardial perfusion and perfusion reserve through the subtraction of labeled and non-labeled images. Imperfect subtraction caused by cardiac or respiratory motion will lead to measurement error. In this work, we examine the potential for myocardial background suppression using a saturation-double-inversion-recovery preparation that is compatible with ASL experiments. In six volunteers, myocardial signal was suppressed to 1.14% 1.24% of its equilibrium value.