Abstract #4489

Assessing Cardiac Kinetics Using Highly Accelerated Free Breathing 2D Through-Time Radial GRAPPA Compared to Cartesian Real-Time and Segmented Cine Imaging

Jeremy D. Collins¹, Bruce S. Spottiswoode², Haris Saybasili³, Mark A. Griswold³,⁴, Nicole Seiberlich³, L. Cort Sommerville⁵, Keyur Parekh¹, Michael Markl⁶,⁷, James C. Carr⁵

¹Radiology, Northwestern University, Chicago, IL, United States; ²Cardiovascular MR R&D, Siemens Healthcare, Chicago, IL, United States; ³Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; ⁴Radiology, Case Western Reserve University, Cleveland, OH, United States; ⁵Radiology, Northwestern University, Chicago, Il, United States; ⁶Radiology, Northwestern University, Chiago, IL, United States; ⁷Biomedical Engineering, Northwestern University, Chicago, IL, United States

This pilot study evaluates the clinical feasibility of highly accelerated radial GRAPPA real-time bSSFP acquisitions for left ventricular diastology, comparing to accelerated Cartesian real-time and segmented bSSFP acquisitions. Real-time GRAPPA acquisitions with effective temporal resolutions as low as 25 msec were clinically feasible, with adequate image quality to identify the blood pool-myocardial boundary with clear separation of diastolic filling phases. Image quality was limited for trabecular assessment, however. The real-time GRAPPA acquisitions were more accurate for diastolic assessment than Cartesian real-time or Cartesian segmented acquisitions compared to echocardiography. Work is ongoing to assess beat-to-beat quantitative differences in left ventricular diastology.