Abstract #3847

Dynamic Quantitative Susceptibility Mapping for Contrast Agent Concentration

Bo Xu¹, Tian Liu², Pascal Spincemaille², Nanda Deepa Thimmappa², Martin R. Prince², Yi Wang¹

¹Biomedical Engineering, Cornell University, Ithaca, NY, United States; ²Weill Cornell Medical College, New York, United States

A dynamic quantitative susceptibility imaging method is presented for 3D imaging of Gadolinium concentration at sub-second frame rate. A multi-echo flow compensated spiral gradient echo is used for data acquisition. Temporal resolution acceleration with constrained evolution reconstruction is used to generate high temporal frame rate. A morphology enabled dipole inversion with nonlinear formulation is used to generate quantitative susceptibility mapping from complex frame images.