Abstract #3687

Effects of a Nutrient-Combination Diet on Cerebral Blood Flow, Metabolites Levels and Brain Diffusion in ApoE4 and ApoE Knockout Mice

Valerio Zerbi¹,², Diane Jansen¹, Maarten Van Beek¹, Roy Haast¹, Andor Veltien³, Laus M. Broersen⁴, Jack JA Van Asten³, Arend Heerschap³, Amanda J. Kiliaan¹

¹Anatomy, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Netherlands; ²Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, Netherlands; ³Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Netherlands; ⁴Nutricia Advanced Medical Nutrition, Centre for Specialised Nutrition, Wageningen, Netherlands, Netherlands

Research into Alzheimers disease (AD) suggests that dietary behavior may affect the course of AD. A specific combination of omega-3 fatty acids with precursors and cofactors in membrane synthesis was developed for the dietary management of AD.