Ashik Amlani1,
Subhadip Ghosh-Ray1, Katherine van Ree1, Andreas Makris2,
Shirley D'Sa2, Peter Ostler2, Nicola Anyamene2,
Anwar R. Padhani1
1Paul
Strickland Scanner Centre, Mount Vernon Cancer Centre, London, Middlesex,
United Kingdom; 2Mount Vernon Cancer Centre, London, United
Kingdom
There are stepwise increases in tissue-normalised SI, ADC values and water:fat ratio when sequentially comparing YBM to RBM and malignant bone marrow disease. The polynomial relationships between both DW-SI and water:fat ratio with ADC values are independent of tumour type allowing an opportunity to set a generally applicable upper ADC limit (threshold) for untreated/relapsed disease.