Nina Tunariu1,
2, David John Collins1, James A. d'Arcy3,
Veronica A. Morgan4, Sharon L. Giles4, Catherine J.
Simpkin4, Timothy A. Yap5, Nandita M. De Souza6
1CR-UK
and EPSRC Cancer Imaging Centre , Institute of Cancer Research & The
Royal Marsden Hospital, Sutton, London, United Kingdom; 2Drug
Development Unit, Institute of Cancer Research & The Royal Marsden
Hospital, Sutton, London, United Kingdom; 3CR-UK and EPSRC Cancer
Imaging Centre, The Institute of Cancer Research, Sutton, London, United
Kingdom; 4CR-UK and EPSRC Cancer Imaging Centre, Institute of
Cancer Research & The Royal Marsden Hospital, Sutton, London, United
Kingdom; 5Section of Medicine, Institute of Cancer Research &
The Royal Marsden Hospital, Sutton, London, United Kingdom; 6CR-UK
and EPSRC Cancer Imaging Centre, Institute of Cancer Research, Sutton,
London, United Kingdom
Intrinsic susceptibility weighted (ISW) MRI and derived R2*measurements have been described as potential tool for tumour hypoxia assessment in prostate and breast cancer. The aim of this study was to measure R2* in normal liver and in liver metastases, compare these measurements and establish their reproducibility.