Yeun-Chung Chang1,
Ang Yuan2, Chia-Hsien Cheng3, Yi Fang Chen4,
Yi-Chien Lu1, Kua-Hung Cho5, Jyh-Horng Chen6
1Department
of Medical Imaging, National Taiwan University Hospital and National Taiwan
University College of Medicine, Taipei, Taiwan, Taiwan; 2Department
of Internal Medicine, National Taiwan University Hospital and National Taiwan
University College of Medicine, Taipei, Taiwan, Taiwan; 3Department
of oncology, National Taiwan
University, Taipei, Taiwan, Taiwan; 4Institute of Clinical
Dentistry, National Taiwan University, Taipei, Taiwan, Taiwan; 5Instrumentation
Resource Center, National Yang-Ming University, Taipei, Taiwan, Taiwan; 6National
Taiwan University, National Taiwan University, Taipei, Taiwan, Taiwan
Combination of both DCE-MRI and DW-MRI provides more comprehensive understanding of change of internal tumor composition. Many preclinical studies have indicated that the addition of various types of antiangiogenic or antivascular therapy to single-dose or fractionated radiotherapy can synergistically improve the response of human and murine tumors to treatment.