Yoshiko Ueno1,
Satoru Takahashi1, Kazuhiro Kitajima1, Tokunori Kimura2,
Ikuo Aoki2, Fumi Kawakami3, Hideaki Miyake4,
Yoshiharu Ohno1, 5, Kazuro Sugimura1
1Department
of Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo,
Japan; 2Toshiba Medical Systems, Ohtawara, Tochigi, Japan; 3Department
of Pathology, Kobe University Graduate School of Medicine, Kobe, Hyogo,
Japan; 4Department of Urology, Kobe University Graduate School of
Medicine, Kobe, Hyogo, Japan; 5Advanced Biomedical Imaging
Research Center, Kobe University Graduate School of Medicine, Kobe, Hyogo,
Japan
For prostate cancer (PCa) detection, DWI with high b-values over 1000 s/mm2 is recently suggested as useful for providing good contrast between cancerous and background tissue, although several limitations were also suggested. In the last decade, computed DWI (cDWI) is proposed as a new technique that produces any b-value images from DWI acquired with at least two different b-values. The aim of our study was therefore to evaluate the ability of cDWI at b=2000 s/mm2 (cDWI2000) for PCa detection as compared with actually obtained DWI at b=1000 (mDWI1000) and b=2000 s/mm2