Abstract #3150

Knowledge-Based Tractography Using Path Finding by Dynamic Programing

Muwei Li¹, J. Tilak Ratnanather², Yajing Zhang¹, Hangyi Jiang¹, Kenichi Oishi¹, Michael I. Miller², Susumu Mori¹

¹The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States; ²Center for Imaging Science, Johns Hopkins University, Baltimore, MD, United States

A knowledge-guided path-finding approach is proposed in this study. Combined with the automated brain segmentation, this approach can automatically generate 106 tracts based on our anatomical knowledge.This tool can be used to investigate tract-specific white matter anatomical states in various brain disorders.