Yuxiang Zhou1,
2, Lingyun Chen2, Xiaojun Sun3, Vipulkumar Patel3,
Jerry S. Wolinsky4, Ponnada A. Narayana3
1Department
of Diagnostic and Interventional Imaging , University of Texas Medical School
at Houston, Houston, TX, United States; 2Department of Diagnostic
& Molucular Imaging, Beaumont Health System, Royal Oak, MI, United
States; 3Department of Diagnostic and Interventional Imaging,
University of Texas Medical School at Houston, Houston, TX, United States; 4Department
of Neurology, University of Texas Medical School at Houston, Houston, TX,
United States
Tagging efficiency plays an important role in absolute CBF quantification based on (pseudo continuous arterial spin labeling (pCASL). In pCASL, the tagging efficiency strongly depends on the subject and other factors. Phase contrast MRA (PCMRA) is used for determining the tagging efficiency in a subject specific manner. Reproducibility of CBF and tagging efficiency were investigated by scanning the subject twice within one hour. No statistically significant differences between the mean of the two measurements was observed, suggesting excellent reproducibility. This study also demonstrates that non-gated PCMRA, which involves shorter scan times, is a reliable method for measuring the tagging efficiency.