Abstract #2955

Non-Linear Modeling of T1, T2 and MWF Developmental Trajectories

Douglas C. Dean III¹, Jonathan O'Muircheartaigh,¹², Lindsay Walker¹, Holly Dirks¹, Nicole Waskiewicz¹, Katie Lehman¹, Beth A. Jerskey¹,³, Sean C. L. Deoni¹

¹Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, RI, United States; ²Dept. of Neuroimaging Sciences, King's College London, Institute of Psychiatry, London, United Kingdom; ³Dept. Oof Psychiatry & Human Behavior, Brown University, Providence , RI, United States

Rapid neurodevelopmental changes can be investigated using magnetic resonance imaging (MRI). An anatomical model of development can be obtained by modeling quantitative maps of healthy infants and toddlers. In this work we modeled regional and whole-brain T1, T2, and MWF maps of healthy children under 5 years of age. This model can be used to characterize normal development and serve as a baseline of typical development.