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Abstract #2845

Differential Diffusivity in Parkinsonism

Mohit Saxena1, S. Senthil Kumaran2, Madhuri Behari1, Vinay Goyal1

1Department of Neurology, All India Institute of Medical Sciences, New Delhi, Delhi, India; 2Department of NMR, All India Institute of Medical Sciences, New Delhi, Delhi, India


Parkinsons Disease presents difficulty in coordinated movements due to loss of dopaminergic neurons in the substantia nigra. We observed a significant loss in the whole brain fibers in PD subjects as compared to in controls. We observed significantly low FA values in the SMA and thalamus.