Ge Zhang1,
Xianlong Wang1, Shilong Lu1, Jinyuan Zhou2,
Zhibo Wen1
1Department
of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou,
Guangdong, China; 2Department of Radiology and Radiological
Science, Johns Hopkins University School of Medicine, Baltimore, MD, United
States
We explored the imaging features of different grades of glioma using Amide Proton Transfer MR Imaging at 3 Tesla. Results showed that the average APT signal intensities of the viable tumor cores were significantly higher than those of peritumoral edema or normal-appearing white matter in both low-grade and high-grade glioma. The average APT signal intensities of the viable tumor cores were significantly higher than in low-grade glioma. APT imaging provides additional diagnostic information to characterize different grade of glioma.