Relevance of Morphological Binary Information for L2 and L1 Total Variation Methods in Quantitative Susceptibility Mapping and Reconstruction Quality Assessment Without Presence of the Ground Truth

Diana Khabipova¹, Yves Wiaux², ³, Rolf Gruetter⁴, ⁵, Jos P. Marques¹, ⁵

Phase imaging has been demonstrated to achieve a good contrast between and within brain tissues at 7T. However, phase imaging suffers from a non-local contrast variation which can be overcome by calculating the underlying magnetic susceptibility maps. As this problem is ill-posed, many regularization methods have been proposed over the past years. In this abstract we do a thorough comparison of some of these methods, focus on the impact of the prior information on the reconstructed susceptibility maps and propose a method to evaluate the quality of the susceptibility reconstruction in the absence of a ground truth.