Jing Guo1,
Sebastian Hirsch2, Rolf Reiter1, Thomas Kroencke1,
Patrick Asbach3, Juergen Braun4, Ingolf Sack1
1Department
of Radiology, Charite - University Medicine Berlin, Berlin, Germany; 2Department
of Radiology, Charit - Universittsmedizin Berlin, Berlin, Germany; 3MVZ
CBF Radiologie, Charite - University Medicine Berlin, Berlin, Germany; 4Department
of Medical Informatics, Charite - University Medicine Berlin, Berlin, Germany
3D multifrequency MRE including nonmagnetic shear wave excitation and least-squares multifrequency inversion is introduced for improving the spatial resolution in abdominal-MRE viscoelasticity maps. The new method is demonstrated in health volunteers and patients with ascites and portal hypertension. All three technical key-points, driver, single-shot wave field acquisition and dual parameter inversion, are new in their application to abdominal MRE and contribute to an improved clinical protocol for the precise and spatially highly resolved mechanical assessment of the liver and the spleen.