Stability of Resting-State Brain Activity Fluctuations Across Time: Evidence from fMRI and MEG

Om Bhatt¹, Jed Meltzer¹, Bernhard Ross¹, J. Jean Chen¹

Magnetoencephalography (MEG) is potentially valuable in clarifying the physiological mechanisms of resting-state fMRI-based functional connectivity. However, MEG and fMRI experiments cannot be performed simultaneously on the same subject. In this work, we present evidence for a stability of intrinsic brain activity across time. This stability is higher in certain brain regions, and higher during eyes-open than in eyes-closed resting state. These findings will enhance our ability to capitalize on the spatially resolved neuro-electric information from MEG to inform resting-state fMRI interpretations of brain activity. Future work will address the link between these spectral features and connectivity.