Abstract #2225

Direct CBF Comparison Between MRI ASL and DSC and Perfusion CT-Scan in Treated Tumor Patients

Marjorie Villien¹,², Do Kien N Guyen¹, Julien Bouvier¹, Cedric Mendoza³, Sylvie Grand³, Louise Fanchon¹, Emmanuel Luc Barbier⁴, Irne Troprs⁵, Jean-Franois Le Bas³, Alexandre Krainik³, Jan M. Warnking¹

¹Grenoble Institut of Neurosciences, INSERM, Grenoble, France; ²Massachusetts General Hospital, Harvard, Charlestown, MA, United States; ³Clinique universitaire de neuroradiologie et d'IRM, CHU Grenoble, Grenoble, France; ⁴Grenoble Institut of Neurosciences, INSERM U836, Grenoble, France; ⁵SFR1, Universit Joseph Fourier, Grenoble, France

The goals of this study were to assess the reproducibility of Dynamic Susceptibility Contrast (DSC) MRI and Perfusion-CT (PCT) and to compare the CBF estimates obtained with DSC, PCT, and Arterial Spin Labeling (ASL). We included patients with cerebral tumor, routinely monitored with these imaging methods. We observed good agreement between DSC and PCT, and poor correlation between DSC and ASL. A more detailed analysis of the present data could yield insights into the respective strengths and weaknesses of each method depending on the vascular properties.