David D. Shin1,
Burak I. Ozyurt2, Thomas T. Liu1
1Center
for Functional MRI, University of California, San Diego, La Jolla, CA, United
States; 2Dept. of Psychiatry, University of California, San Diego,
La Jolla, CA, United States
Since its introduction in 2011 ISMRM, the CBFBIRN Database and Analysis Pipeline (CBFDAP) has processed/stored more than 1300 ASL datasets contributed by 24 research studies. The availability of CBF data from many diverse conditions (e.g. Alzheimers disease, schizophrenia, bipolar disorder, etc.) and associated subject demographics/assessments provides a unique opportunity to explore and mine clinically useful information. In order to facilitate this process, we developed a host of automated group analysis tools and integrated them to the CBFDAP. Three types of group analysis are supported, Path 1: mean gray matter analysis; Path 2: Regional analysis with user-provided ROIs; Path 3: voxel-level standard space analysis. Examples from all three paths are presented.