How to Make Sure You Are Using the Correct Gradient Orientations in Your Diffusion MRI Study

Ben Jeurissen¹, Alexander Leemans², Jan Sijbers¹

Ensuring one is using the correct gradient table in a diffusion MRI study can be a challenging task. Different scanners, file formats and processing tools use different coordinate frame conventions. This can lead to gradient orientations containing an angulation error, which might go unnoticed when small. In this work, we propose a fast and reliable tool to automatically align the gradient table with the corresponding diffusion weighted images, using a metric based on whole brain tractography. Simulations show that sub-degree accuracy and precision is achieved. This tool will be made available during the meeting as a web application.