Abstract #1997

Measurement of Transverse Relaxation Times in Brain Tumors

Akshay Madan¹, Sandeep Ganji¹, Elizabeth A. Maher², Changho Choi³

¹Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States; ²Harold C. Simmons Cancer Center, UT Southwestern Medical Center, Dallas, TX, United States; ³Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States

In this study we performed invivo T₂ measurement of metabolites like N-acetylaspartate, Creatine, Choline and water in glioma patients for comparison with normal brain using single voxel point resolved spectroscopy at multiple echo times at 3T. We calculated T₂ using monoexponential nonlinear fitting of metabolite signal estimates obtained from LCModel.