Elijah George1,
2, Steven Roys1, 3, Jiachen Zhuo1,
Chandler R. Sours4, Jacqueline Janowich1, Teodora
Stoica1, Rao P. Gullapalli1
1Magnetic
Resonance Research Center, University of Maryland School of Medicine,
Baltimore, MD, United States; 2Bioengineering, University of
Maryland, College Park, MD, United States; 3Diagnostic Radiology
& Nuclear Medicne, University of Maryland School of Medicine, Baltimore,
MD, United States; 4Program in Neuroscience, University of
Maryland School of Medicine, Baltimore, MD, United States
Mild traumatic brain injury (mTBI) patients represent 75% of the viable TBI population. The aim of the current study is to carry out a longitudinal evaluation of mTBI by monitoring metabolic markers of mTBI and their evolution over time such that the findings realized herein will aid improved clinical evaluation of the pathology. We combined neuro-metabolic information with neuropsychological test (NPT) data for the purpose of understanding how current metabolic state affects ongoing cognitive capability, and to determine the efficacy of neuro-metabolic information acquired acutely in predicting outcome of mTBI patients.