Quantitative Liver MRI Combining Phase Contrast Imaging, Elastography, and DWI: Assessment of Test-Retest and Post-Prandial Effect. Prospective Study at 3T.

Guido H. Jajamovich¹, Hadrien A. Dyvorne¹, Ersin Bayram², Claudia Donnerhack¹, Richard L. Ehman³, Bachir Taouli¹

Liver blood flow and metabolism can be altered in postprandial state, which may induce changes in quantitative MRI techniques such as phase contrast (PC), MR elastography (MRE) and DWI. In this study, we assess reproducibility in fasting conditions and the post-prandial effect on the following metrics: portal venous blood flow/velocity, liver stiffness measured with MRE and liver ADC measured with DWI in 11 subjects. Portal venous flow/velocity and liver stiffness increased significantly after caloric intake, whereas ADC did not show significant changes.