Abstract #1432

Analysis of Right Ventricular Kinetic Energy in an Acute PAH Animal Model Using 4D Flow MRI.

Alejandro Roldn-Alzate¹, Philip C. Kilgas², Kevin M. Johnson², Oliver Wieben¹,², Christopher J. Francois³

¹Radiology, University of Wisconsin, Madison, WI, United States; ²Medical Physics, University of Wisconsin, Madison, WI, United States; ³Radiology, University of Wisconsin-Madison, Madison, WI, United States

In patients with pulmonary hypertension (PH), blood pressure and resistance in the pulmonary circulation are elevated, leading to decreases in right ventricle (RV) function. The correlation between ventricular-vascular coupling efficiency and non-invasive metrics of PA and RV function in PH is unclear. Results in this pilot study demonstrate the feasibility of 4D flow MRI for quantifying RV kinetic energy in an animal model of acute thromboembolic PH. Future studies will concentrate on the implementation of the technique for the analysis of human PH patients.