Abstract #1422

Comparison of Under-Sampled Cartesian Pulmonary Perfusion MRI Reconstructed with Either View Sharing or HYCR

Scott K. Nagle¹,², Laura C. Bell³, Mark L. Schiebler¹, Christopher J. Francois⁴, James H. Holmes⁵, Sean B. Fain,¹², Kang Wang⁵

¹Radiology, University of Wisconsin, Madison, WI, United States; ²Medical Physics, University of Wisconsin, Madison, WI, United States; ³Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; ⁴Radiology, University of Wisconsin-Madison, Madison, WI, United States; ⁵Global Applied Science Laboratory, GE Healthcare, Madison, WI, United States

Quantitative contrast-enhanced pulmonary perfusion MRI has been limited by the need for high temporal-spatial resolution, full-lung coverage, and the need to scan within a reasonable length breath-hold. The purpose of this work was to compare the performance of 3 different Cartesian under-sampling methods in combination with 2 alternative reconstruction methods to perform whole-chest, time-resolved pulmonary perfusion MRI with isotropic 4mm resolution and 0.5-1s temporal resolution. Qualitative assessment of image quality at peak parenchymal enhancement was comparable. However, quantitative assessment of the contrast enhancement curves showed higher maximum values, steeper up-slopes, and shorter rise-times using HYCR rather than view-sharing reconstruction.