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Abstract #1407

High Resolution Myocardial T1 Mapping Using MOLLI with Parallel Imaging and Compressed Sensing

Xiao Chen1, Bhairav B. Mehta1, Michael Salerno2, 3, Frederick H. Epstein1

1Biomedical Engineering, University of Virginia, Charlottesville, VA, United States; 2Medicine, University of Virginia, Charlottesville, VA, United States; 3Radiology, University of Virginia, Charlottesville, VA, United States


Modified Look-Locker Imaging (MOLLI) is routinely used for T1 mapping of the left ventricle. High resolution MOLLI requires fast imaging to remain free of artifacts due to cardiorespiratory motion. The combination of parallel imaging and compressed sensing (CS) has been used to accelerate cardiac cine and perfusion imaging but not MOLLI. We developed an algorithm that combines parallel SENSE and CS kt-Sparsity and Low Rank (kt-SLR) and applied it to accelerate MOLLI to achieve high resolution (1.21.2 mm2) T1 mapping using a standard breathhold clinical protocol (17 heartbeats).