Supplemental Oxygenation and Hyper Ventilation for Accelerated 3D Late Gadolinium Enhancement Imaging of Left Ventricle Within a Single Breath Hold

Sbastien Roujol¹, Tamer A. Basha¹, Mehmet Akakaya¹, Murilo Foppa¹, Kraig V. Kissinger¹, Beth Goddu¹, Sophie J. Berg¹, Warren J. Manning¹, ², Reza Nezafat¹

2D Late gadolinium enhancement (LGE) MRI is commonly used for assessment of scar in the left ventricle. 3D LGE is an alternative approach where the entire LV is imaged in a single scan, allowing higher spatial resolution and better coverage. However, 3D scans are usually long, require free-breathing acquisitions and are respiratory gated using a navigator. Navigator gating will increase the scan time by 2-3 times. In this study, we sought to investigate the feasibility of an accelerated 3D LGE acquisition within one single prolonged breath hold using pre-oxygenation and hyperventilation.