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Abstract #1356

4D Flow-Sensitive MRI Pulmonary Artery Pulse Wave Velocity in Pulmonary Arterial Hypertension

Christopher J. Franois1, Alejandro Roldn-Alzate1, Andrew L. Wentland1, Heidi B. Kellihan2, Naomi C. Chesler3, Oliver Wieben1, 4

1Radiology, University of Wisconsin, Madison, WI, United States; 2Veterinary Medicine, University of Wisconsin, Madison, WI, United States; 3Biomedical Engineering, University of Wisconsin, Madison, WI, United States; 4Medical Physics, University of Wisconsin, Madison, WI, United States


4D flow-sensitive MRI was used to calculate pulmonary artery pulse wave velocity (PWV) in a canine model of acute thromboembolic pulmonary arterial hypertension (PAH). PWV significantly increased with PAH and was strongly correlated with mean pulmonary arterial pressure.