Abstract #1266

Improving Visualization of Mouse Brain Nuclei in Manganese-Enhanced MRI Using Super-Resolution Reconstruction

Esben Plenge¹, Dana S. Poole², Dirk H.J. Poot³, Egbert A.J.F. Lakke⁴, Wiro J. Niessen³,⁵, Erik Meijering³, Louise van der Weerd²,⁶

¹The Biomedical Imaging Group (BIGR), Radiology & Medical Informatics, Erasmus MC University Medical Center, Rotterdam , Netherlands; ²Radiology, Leiden University Medical Center,, Leiden, Netherlands; ³The Biomedical Imaging Group (BIGR), Radiology & Medical Informatics, Erasmus MC University Medical Center, Rotterdam, Netherlands; ⁴Anatomy, Leiden University Medical Center, Leiden, Netherlands; ⁵Quantitative Imaging Group, Dept. of Imaging Science and Technology, Faculty of Applied Sciences, Delft University of Technology, Delft, Netherlands; ⁶Human Genetics, Leiden University Medical Center, Leiden, Netherlands

In this study we demonstrate how super-resolution reconstruction (SRR) can be used to overcome the anisotropy issue and produce high-resolution isotropic volumes in acquisition times compatible with in-vivo experiments.