Abstract #1244

Brain Temperature and Brain Energy Changes During Tasks and Light Anesthesia: Estimation with MRS

Yoshichika Yoshioka¹,², Hiroshi Oikawa³, Yoshiyuki Kanbara⁴, Yutaka Matsumura⁴, Takashi Inoue⁵, Yutaka Shinohe⁶, Shigeharu Joh⁶, Tsuyoshi Matsuda⁷, Akira Nabatani⁸, Junji Seki⁹

¹Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Osaka, Japan; ²Center for Information and Neural Networks (CiNet), National Institute of Information and Communications Technology, and Osaka University, Suita, Osaka, Japan; ³Radiology, Ninohe Hospital, Ninohe, Iwate, Japan; ⁴High Field MRI Research Institute, Iwate Medical University, Takizawa, Iwate, Japan; ⁵Neurosurgery, Kohnan Hospital, Sendai, Miyagi, Japan; ⁶Dental Anesthesiology, Iwate Medical University, Morioka, Iwate, Japan; ⁷Applied Science Laboratory, GE Healthcare Japan, Hino, Tokyo, Japan; ⁸Madical Imaging Strategic Planning Div., Canon, Ohtaku, Tokyo, Japan; ⁹National Cerebral and Cardiovascular Center, Suita, Osaka, Japan

Physiological human brain temperatures have been measured by MRS. However, it is not clear whether the brain temperature rises or falls during brain activations. We have tried to monitor brain temperature changes during exercises and some other maneuvers. We found that the brain temperatures fall during light tasks such as hand grasp, tongue stimulation, and sedation. We also could estimate the brain energy decrease during sedation as 0.2 W (estimated as a whole brain) with brain temperature changes. The energy difference between arousal and sedation in our case was about 1 % of the energy that brain needs.