Abstract #1172

Disrupted Functional Brain Connectivity in the Salience Network of Post Stroke Depression Patients

Ji-Young Kim¹, Seong-Uk Jin², Jee-Hye Seo², Jang Woo Park², Jongsu Baek², Moon Han², Kyung-Eun Jang², Young-Hwan Lee*³, Yongmin Chang⁴,⁵

¹Medical Science, Kyungpook National University School of Medicine, Daegu, Korea; ²Medical & Biological Engineering, Kyungpook National University, Daegu, Korea; ³Radiology, Catholic University Medical Center, Daegu, Korea; ⁴Radiology, Kyungpook National University, Daegu, Korea; ⁵Molecular Medicine, Kyungpook National University , Daegy, Korea

Poststroke depression (PSD), a common and important neuropsychiatric sequela of stroke, is known to be a multifactorial process. In this study, using resting-state fMRI (rs-fMRI), we investigate possible alteration in functional connectivity (FC) in association with PSD in the salience network (SN), which was most functionally relevant to depression.