Relationship Analysis of Axial and Radial Diffusivities May Be Helpful in Discriminating Tumor-Infiltrating Edema from Pure Vasogenic Edema

Zhigang Min¹, ², Chen Niu¹, Ming Zhang¹

Due to the infiltration of tumor cells, the axons and myelin were destroyed. tumor-infiltrating edema has greater radial diffusivities than pure vasogenic edema. But the direct comparisons of ˡ will be influenced by the degree of edema and can not reveal the diffusion characteristics induced by damaged axons and myelin. We compared the relationships of ˡ and ˡ in pure vasogenic edema and tumor-infiltrating edema and found the significant different between the two types of edema. RCˡ-ˡ showed more effective than other metrics in discriminating tumor-infiltrated edema from pure vasogenic edema.