Abstract #1111

Age-Related Metabolite Changes in Healthy Spinal Cord: A 1H MRS Study at 3T

Khaled Abdel-Aziz¹, Bhavana Solanky¹, Marios C. Yiannakas¹, Claudia Angela M. Wheeler-Kingshott², Alan Thompson¹, Olga Ciccarelli³

¹NMR Research Unit, Queen Square MS Centre, UCL, London, United Kingdom; ²NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL, London, United Kingdom; ³NMR Research Unit, Queen Square MS Centre, UCL Institute of Neurology, London, United Kingdom

Several studies have examined the changes in brain metabolites quantified with MRS as a consequence of normal aging but no such studies have yet been performed in the spinal cord. This study has examined the effect of age on commonly quantified spinal cord metabolites.