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Abstract #1015

Shifting Characteristics of Upper Motor Neuron Revealed by Voxel-Based Morphometry in Amyotrophic Lateral Sclerosis

Qiuli Zhang1, Cuiping Mao1, Ming Zhang1, Jingxia Dang2, Jiaoting Jin2

1Department of Radiology, the First Affiliated Hospital of Medcine College of Xi'an JiaoTong University, Xi'An, ShaanXi, China; 2Department of Neurology, the First Affiliated Hospital of Medcine College of Xi'an JiaoTong University, Xi'An, ShaanXi, China


The underlying mechanisms of degeneration process in ALS are still unclear. This study use FSL-VBM in order to detect potential spread characteristics of upper motor neurons, through the topography of gray matter changes.