Timo
Liimatainen1, Alejandra Sierra1, Hanne Hakkarainen1,
Djaudat Idiyatullin2, Christine Storino2, Silvia Mangia2,
Olli Grhn1, Michael Garwood2, Shalom Michaeli2
1A.I.Virtanen
Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Fi,
Finland; 2Center for Magnetic Resonance Research, University of
Minnesota, Minneapolis, MN, United States
Relaxation Along a Fictitious Field (RAFF) was used to characterize MRI tissue contrast in a rotating frames of rank n, where n was varied between 1 and 5. Relaxation times maps in high-rank rotating frames correlate with myelin content in the rat brain ex vivo better than T1, T2, T1&[rho], T2&[rho] or MT. The RAFFn provides high potential for mapping of myelination in the brain.