Meijin Lin1,
Anand Kumar1, Shaolin Yang1, 2
1Department
of Psychiatry, University of Illinois at Chicago, Chicago, IL, United States;
2Department of Radiology, University of Illinois at Chicago, Chicago,
IL, United States
In this report, two-dimensional (2D) J-resolved spectroscopy using localization by adiabatic selective refocusing (LASER), named as J-resolved LASER, was introduced to suppress the chemical shift artifacts, additional J-refocused artifactual peaks resulted from spatially dependent J-coupling evolution, and the sensitivity to radiofrequency field inhomogeneity. Phantom and human experiments were performed to demonstrate the feasibility and advantages of J-resolved LASER spectroscopy over conventional J-resolved spectroscopy (JPRESS).