1CUBRIC,
School of Psychology, Cardiff University, Cardiff, South Glamorgan, United
Kingdom; 2School of Computer Science, Cardiff University, Cardiff,
South Glamorgan, United Kingdom; 3School of Dentistry, Cardiff
University, Cardiff, South Glamorgan, United Kingdom
We propose a novel method for fully automated segmentation of large tractography datasets. By measuring the modes and magnitudes of streamline shape variation within the brain, we are able to build a white matter shape space in which streamlines belonging to particular anatomical features consistently project to distinct sub-regions; thus allowing us to segment unseen streamline data by observing their projected positions. An additional advantage of this technique is the computationally trivial nature of the projection process which, when compared to other techniques with similar aims, significantly reduces both run time and memory footprint.