1Center
for MR-Research, University Childrens Hospital, Zrich, Switzerland; 2Center
for Integrative Human Physiology (ZIHP), University of Zrich, Zrich ,
Switzerland; 3Center for Integrative Human Physiology (ZIHP),
University of Zrich, Zrich, Switzerland; 4Institute of
Psychology, University of Zrich, Zrich, Switzerland; 5Institute
of Neuroradiology, University of Zrich, Zrich, Switzerland; 6Department
of Child & Adolescent Psychiatry, University of Zrich, Zrich,
Switzerland; 7Psychiatric University Hospital, University of
Zrich, Zrich, Switzerland; 8Central Institute of Mental Health
Mannheim, Medical Faculty Mannheim/ Heidelberg University, Mannheim, Germany
Since working memory deficits play an important role in ADHD we developed a spatial working memory task to examine differences in brain activity between adults and children with ADHD and controls. In a fMRI study we investigated adults and children with and without ADHD to understand the underlying developmental deficits seen in ADHD. Our results suggest that the working memory networks are not yet fully developed in children and that ADHD subjects do not recruit a larger network to handle increased working memory demand, unlike control subjects.