Abstract #0525

Retinotopic-Specific Changes of Cerebral Blood Flow and Grey Matter in Visual Cortex of Patients with Glaucoma

Bo Wang¹, Shaodan Zhang²,³, Y Xie², Ningli Wang², Chun Zhang³, Xiaohong Joe Zhou⁴, Yan Zhuo¹

¹State Key Lab of Brain & Cognitive Science, Institute of Biophysics, Chinese Academy of China, Beijing, China; ²Beijing Tongren Hospital affiliated to Capital Medical University, Beijing, China; ³Peking University Third Hospital, Beijing, China; ⁴University of Illinois Medical Center at Chicago, Chicago, IL, United States

Differences were observed in blood flow, morphology and metabolites in the visual cortex between POAG (patients with primary open angle glaucoma) patients and age-matched normal controls, suggesting that rCBF and/or VBM may be used as a specific and sensitive marker in assessing brain injury in glaucoma patients.