Use of Deformable Registration for Quantification of Cardiac Perfusion in Patients with Arrhythmia

Devavrat Likhite¹, Ganesh Adluru¹, Christopher J. McGann², Edward V.R. DiBella¹

Dynamic contrast enhanced MRI is maturing as a tool in contemporary cardiovascular medicine and quantifying cardiac perfusion is becoming clinically relevant. However, the use of ECG gating is a problem under certain conditions and can challenge current quantification methods. Here we use self-gated approach, which increases the processing complications as it requires additional steps to correct for cardiac motion present. This work presents the use of deformable registration that improves the accuracy quantification of cardiac perfusion .The quantification results obtained from the registered ungated acquisitions show good correlation with those from gated acquisitions.