Michael Salerno1,
2, Yang Yang3, Sujith Kuruvilla1, Craig H. Meyer3,
Christopher M. Kramer, 12
1Medicine,
Cardiology, University of Virginia, Charlottesville, VA, United States; 2Department
of Radiology, University of Virginia, Charlottesville, VA, United States; 3Biomedical
Engineering, University of Virginia, Charlottesville, VA, United States
We present our initial clinical experience using a newly developed quantitative spiral perfusion pulse sequence for adenosine stress CMR in patients with coronary artery disease. High resolution perfusion images and pixel-wise maps of absolute myocardial perfusion can be obtained with this pulse sequence without any time penalty during data acquisition. In normal subjects the resting perfusion is near 1mL/g/min as expected. In two patients who underwent cardiac catheterization there was excellent correlation between regions of reduced stress perfusion and obstructive coronary artery disease..