Abstract #0212

Subcortical Volumetric Differences in Children with Sickle Cell Disease and Silent Infarction

Jamie M. Kawadler¹, Jonathan D. Clayden², Fenella J. Kirkham³, Christopher A. Clark²

¹Imaging & Biophysics Unit, UCL Institute of Child Health, London, United Kingdom; ²Imaging & Biophysics Unit, University College London, London, United Kingdom; ³Neurosciences Unit, UCL Institute of Child Health, London, United Kingdom

This work investigates for the first time specific subcortical structure volumes in children and adolescents with sickle cell disease, which has been shown to affect cortical grey matter and deep white matter.