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Abstract #0205

Multi-Delay Multi-Parametric Arterial Spin-Labeled Perfusion MRI in Acute Ischemic Stroke Comparison with Dynamic Susceptibility Contrast Enhanced Perfusion Imaging

Danny J.J. Wang1, 2, David S. Liebeskind1, Joe X. Qiao2, Matthias Gnther3, Whitney B. Pope2, Jeffrey L. Saver1, Noriko Salamon2, Jeffry R. Alger1, 2

1Neurology, UCLA, Los Angeles, CA, United States; 2Radiology, UCLA, Los Angeles, CA, United States; 3Institute for Medical Image Computing, University of Bremen, Bremen, Germany


A novel multi-delay multi-parametric pseudo-continuous ASL (pCASL) protocol was presented. Its accuracy was evaluated by comparison with dynamic susceptibility contrast (DSC) enhanced perfusion MRI in 29 patients with acute and subacute ischemic stroke. Consistent results between multiple hemodynamic parameters derived using ASL and DSC were demonstrated.