Abstract #0186

Multicenter Evaluation of Dynamic Three-Dimensional Whole-Heart Myocardial Perfusion Imaging at 3.0 Tesla for the Detection of Coronary Artery Disease Defined by Fractional Flow Reserve

Robert Manka¹,², Rolf Gebker³, Lukas Wissmann¹, Roy Jogiya⁴, Manish Motawani⁵, Michael Frick⁶, Sebastian Reinartz⁶, Bernhard Schnackenburg⁷, Eike Nagel⁴, Sven Plein⁵, Sebastian Kozerke¹

¹University and ETH Zurich, Zurich, Switzerland; ²University Hospital Zurich, Zurich, Switzerland; ³German Heart Institute Berlin, Berlin, Germany; ⁴King's College London, London, United Kingdom; ⁵University of Leeds, Leeds, United Kingdom; ⁶University Hospital RWTH Aachen, Aachen, Germany; ⁷Philips Healthcare, Clinical Sciences, Berlin, Germany

Cardiac magnetic resonance imaging enables noninvasive assessment of myocardial perfusion. However, standard 2D multi-slice CMR perfusion techniques only provide limited coverage and hence prohibit computation of myocardial ischemic burden. Recently, 3D CMR perfusion has proven highly diagnostic in two single-center studies. In this preliminary assessment of our multi-center study 3D CMR perfusion imaging proved highly diagnostic for the detection of functionally significant CAD as defined by FFR.