Adiabatic Multi Echo Spectroscopic ImagiNG (AMESING) for Boosted 31P Sensitivity at 7 Tesla

Wybe J.M. van der Kemp¹, Vincent O Boer¹, Peter R Luijten¹, Dennis W.J. Klomp¹

For metabolites where T2 values are an order of magnitude larger than T2* effects, as is the case for 31P MRS in many locations in the human body at high fields, multi echo sequences can boost sensitivity. Here we show the potential of Adiabatic Multi Echo Spectroscopic Imaging with spherical k-space sampling at 7 Tesla. We tested the sequence for 31P MRSI on the calf muscle and the human breast of healthy volunteers. SNR weighted sum spectra that were acquired had an SNR of up to 2 times higher than the SNR of the FID spectra