Houshang Amiri1, 2, Morteza Mahmoudi3, Valerio Zerbi1, 4, Arend Heerschap1
1Department of Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; 2Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; 3National Cell Bank, Pasteur Institute of Iran, Tehran, Iran; 4Department of Anatomy, , Donders Centre for Neurosciences, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
We have given a comprehensive overview of the current developments in Alzheimer's disease (AD) and focused on the most recent advances in the theranosis strategies using magnetic nanoparticles (MNPs). Functionalized MNPs also have been introduced as smart drug delivery systems. Finally we have discussed state-of-the-art in MRI to track MNPs over time with a special emphasis on the molecular/cellular imaging technique.