Cristbal Martn Serrano Garca1, 2, Francisco Barrera3, Hugo Vidal4, Carlos Riquelme4, Pilar Labb3, Jessica Liberona5, Marco Arrese3, Francisco Cruz4, Clau
1Faculty of Medicine, Pontificia Universidad Catlica de Chile, Santiago, Regin Metropolitana, Chile; 2Biomedical Imaging Center, Pontificia Universidad Catlica de Chile, Santiago, Regin Metropolitana, Chile; 3Gastroenterology, Pontificia Universidad Catlica de Chile, Santiago, Regin Metropolitana, Chile; 4Radiology, Pontificia Universidad Catlica de Chile, Santiago, Regin Metropolitana, Chile; 5Nutrition & Diabetes, Pontificia Universidad Catlica de Chile, Santiago, Regin Metropolitana, Chile; 6Electrical Engineering, Pontificia Universidad Catlica de Chile, Santiago, Regin Metropolitana, Chile
Intra abdominal fat depots has previously been associated with liver fibrosis on non alcoholic fatty liver disease (NAFLD) patients. In this study we evaluated different imaging biomarkers associated with liver fibrosis/cirrhosis in type 2 diabetes mellitus (DM2) patients. For this, we evaluated volumetric quantification of visceral adipose tissue (VAT), and subcutaneous adipose tissue (SAT) using MR; volumetric quantification of abdominal fat depots with anthropometric indexes, like Body Mass Index (BMI) and Waist Circumference (WC); Transient Elastography (TrE) using Acoustic Radiation Force Impulse (ARFI), and clinical diagnosis based on different MR images. Results suggest that DM2 patients with increasing ARFI and largest amount of VAT might be associated with progression of liver fibrosis.