Christopher J. Franois1, Valentina Taviani2, Jennifer L. Rehm3, Christopher J. Hardy4, Ellen L. Connor3, Scott B. Reeder1, 2
1Radiology, University of Wisconsin, Madison, WI, United States; 2Medical Physics, University of Wisconsin, Madison, WI, United States; 3Pediatrics, University of Wisconsin, Madison, WI, United States; 4GE Global Research, General Electric, Niskayuna, NY, United States
Vascular stiffness is one of the earliest predictors of future cardiovascular disease (CVD). However, it is incompletely understood how various risk factors for CVD lead to vascular stiffening. Emerging evidence suggests that hepatic steatosis may play an important role in the development of CVD in adults. In this study we demonstrate the feasibility of assessing pulse wave velocity (PWV), a well established bio marker of vascular stiffness, hepatic fat fraction (HFF), visceral adipose tissue (VAT) and subcutaneous adipose tissue (SCAT) in adolescent girls with risk factors for metabolic syndrome.