Mahdi S. Rahimi1, Kang Wang2, James H. Holmes2, Jean H. Brittain2, Scott B. Reeder1, 3, Frank R. Korosec3, 4
1Biomedical Engineering, University of Wisconsin, Madison, WI, United States; 2Global Applied Science Laboratory, GE Healthcare, Madison, WI, United States; 3Radiology, University of Wisconsin, Madison, WI, United States; 4Medical Physics, University of Wisconsin, Madison, WI, United States
Dynamic Contrast Enhanced (DCE) liver perfusion imaging is a powerful tool for detection and assessment of liver lesions, including hepatocellular carcinoma (HCC). In this work, The IVD-HYCR method is improved by using fluoro-triggering and enabling continuous scanning during the passage of the contrast agent with retrospective identification of multiple breath-hold start times and durations, increasing the methods ability to accurately and consistently acquire high frame-rate images with optimal contrast timing. Continuous scanning during multiple breath-holds and use of data sharing enables acquisition of high spatial and temporal resolution images and numerous time frames, permitting more complete assessment of contrast dynamics.