Abstract #3783

Myocardial T1 Mapping Using a Faster Modified Look-Locker Inversion-Recovery (Fast-MOLLI) Method on 3T MRI : Quantification of Myocardial Fibrosis in Dilated Cardiomyopathy (DCM)

Yoshiaki Morita¹, Naoaki Yamada¹, Teruo Noguchi², Hiromi Hashimura¹, Suzu Kanzaki¹, Masahiro Higashi¹, Hiroaki Naito¹, Katsutoshi Murata³, Andreas Greiser⁴

¹Department of Radiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan; ²Division of Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan; ³Siemens Japan K.K., Tokyo, Japan; ⁴Siemens AG, Erlangen, Germany

Late gadolinium enhancement (LGE) is the widely used method to evaluate the myocardial fibrosis in various heart diseases. However, the standard LGE using null-point method has a limitation in diagnosis of diffuse interstitial fibrosis. This study demonstrated that pre-contrast and post-contrast myocardial T1 mapping using a faster MOLLI method enable direct myocardial signal quantification and can help to evaluate the diffuse fibrotic change even that show apparently unenhanced myocardium on LGE images, in patients with dilated cardiomyopathy (DCM).